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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Cold agglutinin disease


Other Names for this Disease
  • Anemia, hemolytic, cold antibody
  • CAD
  • CAS
  • Chronic cold agglutinin disease
  • Cold agglutinin syndrome
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Inheritance

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Is cold agglutinin disease inherited?

Cold agglutinin disease is not an inherited condition. It is designated as either primary (unknown cause) or secondary (associated with or caused by another condition). In some cases, cold agglutinin may be multifactorial which means that multiple environmental factors and genes likely interact to predispose a person to developing the condition.[1] However, to our knowledge, no disease-causing genes have been identified and no familial cases have been reported.
Last updated: 5/6/2015

References
  1. Marc Michel. Cold agglutinin disease. Orphanet. August, 2010; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=56425. Accessed 5/15/2014.


Other Names for this Disease
  • Anemia, hemolytic, cold antibody
  • CAD
  • CAS
  • Chronic cold agglutinin disease
  • Cold agglutinin syndrome
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.