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Diseases

Genetic and Rare Diseases Information Center (GARD)

Common variable immunodeficiency


Other Names for this Disease
  • CVID
  • Common variable hypogamma-globulinemia
  • Hypogamma-globulinemia, acquired
  • Immunoglobulin deficiency, late-onset
  • Common variable immune deficiency
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Treatment

Newline Maker

How might common variable immunodeficiency be treated? 

The main treatment for common variable immunodeficiency (CVID) is Ig replacement therapy, which stops the cycle of recurrent infections. Ig may be taken intravenously (through the vein) or subcutaneously (by injection). Adverse reactions to Ig must be monitored during therapy.

Ig therapy is effective in most people, leading to less frequent infections and arthritic symptoms. However, gastrointestinal (digestive) symptoms have little improvement with IVIG. In some people wwith CVID and severe autoimmune disease, steroids or other immunosuppressive drugs in addition to Ig therapy may be needed.[1]

Detailed information about the management of CVID can be viewed on Medscape Reference's Web site.
Last updated: 3/14/2016

References
  1. Robert A Schwartz. Common Variable immunodeficiency. Medscape Reference. May 28, 2015; http://emedicine.medscape.com/article/1051103-overview.


GARD Video Tutorial

  • Finding Treatment Information - A video developed by GARD Information Specialists that explains how you can find information about treatment for a rare disease.

    Finding Treatment Information

Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Common variable immunodeficiency. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
  • The Research Portfolio Online Reporting Tool (RePORT) provides access to reports, data, and analyses of research activities at the National Institutes of Health (NIH), including information on NIH expenditures and the results of NIH-supported research. Although these projects may not conduct studies on humans, you may want to contact the investigators to learn more. To search for studies, enter the disease name in the "Text Search" box. Then click "Submit Query".
Other Names for this Disease
  • CVID
  • Common variable hypogamma-globulinemia
  • Hypogamma-globulinemia, acquired
  • Immunoglobulin deficiency, late-onset
  • Common variable immune deficiency
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.