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Diseases

Genetic and Rare Diseases Information Center (GARD)

Cramp-fasciculation syndrome


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Cause

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What causes cramp-fasciculation syndrome?

In many cases, the exact underlying cause of cramp-fasciculation syndrome (CFS) is unknown (idiopathic). In general, it is thought to be related to abnormal excitability (overactivity) of peripheral neurons.[1]

Some cases of CFS are associated with:[1]
Last updated: 7/14/2015

References
  1. Shimatani Y, Nodera H, Shibuta Y, Miyazaki Y, Misawa S, Kuwabara S, Kaji R. Abnormal gating of axonal slow potassium current in cramp-fasciculation syndrome. Clin Neurophysiol. June 2015; 126(6):1246-1254.


See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.