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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Cramp-fasciculation syndrome


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Treatment

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How might cramp-fasciculation syndrome be treated?

There is limited information in the medical literature about the treatment of cramp-fasciculation syndrome (CFS). Much of what is available describes individual cases. Decisions regarding treatment should be carefully considered and discussed with a knowledgeable healthcare provider.

Some people with cramp-fasciculation syndrome improve without treatment. Treatment with carbamazepine, gabapentin, or pregabalin (medications that reduce the hyper-excitability of nerves) was described as helpful in improving symptoms in individual cases.[1] Immunosuppressive therapy (e.g., prednisone) has been used to treat cases of CFS that did not respond to other treatments.[1] For severe cases, additional treatment options may be considered.
Last updated: 5/8/2014

References
  1. Liewluck T, Klein CJ, Jones LK Jr. Cramp-fasciculation syndrome in patients with and without neural autoantibodies. March, 2014; 49(3):351-356. Accessed 5/12/2014.


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