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Diseases

Genetic and Rare Diseases Information Center (GARD)

Crouzon syndrome


Other Names for this Disease
  • Craniofacial dysostosis type 1
  • CFD1
  • Crouzon craniofacial dysostosis
  • Crouzon disease
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Inheritance

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How is Crouzon syndrome inherited?

Crouzon syndrome is inherited in an autosomal dominant manner. This means that having a change (mutation) in only one copy of the responsible gene in each cell is enough to cause features of the condition.

There is nothing that either parent can do, before or during a pregnancy, to cause a child to be born with Crouzon syndrome.

In some cases, an affected person inherits the mutated gene from an affected parent. In other cases, the mutation occurs for the first time in a person with no family history of the condition. This is called a de novo mutation.

When a person with a mutation that causes an autosomal dominant condition has children, each child has a 50% (1 in 2) chance to inherit that mutation.
Last updated: 6/8/2016

References
  1. Crouzon syndrome. Genetics Home Reference. February 2008; http://ghr.nlm.nih.gov/condition/crouzon-syndrome. Accessed 11/7/2015.


Other Names for this Disease
  • Craniofacial dysostosis type 1
  • CFD1
  • Crouzon craniofacial dysostosis
  • Crouzon disease
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.