Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Dubin-Johnson syndrome


Other Names for this Disease
  • Chronic Idiopathic Jaundice
  • Conjugated Hyperbilirubinemia
  • DJS
  • Dubin-Sprinz disease
  • Hyperbilirubinemia 2
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Dubin-Johnson syndrome is a type of hereditary hyperbilirubinemia with a relatively benign course.[1] Symptoms may include a yellowish color to the skin (jaundice), and a liver that is sometimes enlarged and tender.[2]  The symptoms often do not present until puberty or adulthood. The syndrome interferes with the body's ability to move bilirubin from the liver. In most cases, treatment is not required.[3] 
Last updated: 12/19/2008

References

  1. Habashi SL, Lambiase LR, MK Anand, KJ Mishark, Nguyen C . Dubin-Johnson Syndrome. eMedicine. October 10, 2006; http://emedicine.medscape.com/article/173517-overview. Accessed 12/19/2008.
  2. Dubin Johnson Syndrome. National Organization for Rare Disorders (NORD). 2007; http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Dubin%20Johnson%20Syndrome. Accessed 12/19/2008.
  3. Dugdale, DC. Dubin-Johnson syndrome. MedlinePlus. July 22, 2008; http://www.nlm.nih.gov/medlineplus/ency/article/000242.htm. Accessed 12/19/2008.
GARD Video Tutorials
GARD Video Tutorials
Learn how to find information on treatment, research, specialists, and more.
Your Questions Answered
Your Questions Answered
View questions about this condition answered by GARD Information Specialists. You can also submit a new question.

Basic Information

  • Genetics Home Reference (GHR) contains information on Dubin-Johnson syndrome. This website is maintained by the National Library of Medicine.
  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.

In Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Dubin-Johnson syndrome. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Chronic Idiopathic Jaundice
  • Conjugated Hyperbilirubinemia
  • DJS
  • Dubin-Sprinz disease
  • Hyperbilirubinemia 2
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.