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Diseases

Genetic and Rare Diseases Information Center (GARD)

Forbes Albright syndrome


Other Names for this Disease
  • Amenorrhea-galactorrhea, nonpuerperal
  • Galactorrhea-amenorrhea syndrome
  • Nonpuerperal galactorrhea
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Overview

Forbes Albright Syndrome is a rare endocrine disorder characterized by abnormally high levels of prolactin due to a tumor in the pituitary gland.[1] Prolactin is a hormone released by the pituitary gland which stimulates breast development and milk production in women.[2] Symptoms of Forbes-Albright syndrome include the production and secretion of milk from the breasts in the absence of childbirth or nursing (galactorrhea) and the absence of a regular menstrual period (amenorrhea). Affected women may also have an unusual pattern of body hair and reduced sexual drive.[1] Due to the rarity of the condition, it is unclear if Forbes Albright Syndrome is inherited; however, the condition can affect more than one family member which suggests there may be a genetic component in some cases.[3] Treatment may consist of surgery to remove the pituitary tumor and/or certain medications to lower prolactin levels.[1]
Last updated: 1/26/2016

References

  1. Chiari Frommel Syndrome. NORD. 2003; https://rarediseases.org/rare-diseases/chiari-frommel-syndrome/.
  2. Prolactin blood test. MedlinePlus. 2014; https://www.nlm.nih.gov/medlineplus/ency/article/003718.htm.
  3. AMENORRHEA-GALACTORRHEA SYNDROME. OMIM. 1994; http://www.omim.org/entry/104600.
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In Depth Information

  • Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Forbes Albright syndrome. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Amenorrhea-galactorrhea, nonpuerperal
  • Galactorrhea-amenorrhea syndrome
  • Nonpuerperal galactorrhea
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.