Alzheimer disease familial
Other Names for this Disease
- Familial Alzheimer disease
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Regarding the gene mutated the familial forms of AD are subdivided in several subtypes:
• AD1 caused by mutations in the amyloid precursor protein (APP) gene
• AD3 caused by mutations in the presenilin-1 gene (PSEN1) gene
• AD4 caused by mutations in the PSEN2 gene.
The condition known as late-onset familial AD includes only the subtype AD2 and it is associated with the APOE*4 allele on chromosome 19. This condition results in an increased risk of having AD.
Last updated: 9/30/2015
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- The National Institute on Aging (NIA) leads a national program of research on the biomedical, social, and behavioral aspects of the aging process; the prevention of age-related diseases and disabilities; and the promotion of a better quality of life for all older Americans. Click on the link to view information on this topic.
- The National Institutes of Health (NIH) has developed a fact sheet on Alzheimer's disease. To view this fact sheet, click on the link above.
- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Alzheimer disease familial. Click on the link to view a sample search on this topic.
- The Alzherimer's Association provides videos and information to help kids and teens deal with the emotions and reactions that are common when a loved one is diagnosed with Alzheimer’s. Click on Alzheimer's Association to view these resources.
- NIH News: Scientists Report Important Step in Biomarker Testing for Alzheimer's Disease. National Institute on Aging (NIA). March 17, 2009.
- Learn how Alzheimer's disease affects the brain through the Alzheimer's Association's interactive Brain Tour