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Diseases

Genetic and Rare Diseases Information Center (GARD)

Endometrial stromal sarcoma


Other Names for this Disease
  • ESS
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Overview

Endometrial stromal sarcoma is a rare form of cancer that occurs due to abnormal and uncontrolled cell growth in the uterus. Endometrial stromal sarcoma, specifically, develops in the supporting connective tissue (stroma) of the uterus. Signs and symptoms of the condition include abnormal uterine bleeding (i.e. bleeding that is not part of menstrual periods or bleeding after menopause); abdominal pain and/or distension; and frequent urination. The exact underlying cause of endometrial stromal sarcoma is currently unknown. Most cases occur sporadically in people with no family history of the condition. Treatment varies based on the severity of the condition but may include surgery, radiation therapy, chemotherapy, and/or hormone therapy.[1][2][3]
Last updated: 2/15/2016

References

  1. Rauh-Hain JA, del Carmen MG. Endometrial stromal sarcoma: a systematic review. Obstet Gynecol. September 2013; 122(3):676-683.
  2. Uterine Sarcoma. American Cancer Society. February 2016; http://www.cancer.org/cancer/uterinesarcoma/index.
  3. Uterine Sarcoma Treatment (PDQ®). National Cancer Institute. July 2015; http://www.cancer.gov/types/uterine/patient/uterine-sarcoma-treatment-pdq#section/_7.
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Basic Information

  • The American Cancer Society provides information on Endometrial stromal sarcoma. Please click on the link to access this resource.
  • The National Cancer Institute provides the most current information on cancer for patients, health professionals, and the general public.

In Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Endometrial stromal sarcoma. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • ESS
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.