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Diseases

Genetic and Rare Diseases Information Center (GARD)

Necrotizing fasciitis


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Treatment

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How might necrotizing fasciitis be treated?

Accurate and prompt diagnosis, treatment with intravenous (IV) antibiotics, and surgery to remove dead tissue are all important for treating necrotizing fasciitis. Since the blood supply to the infected tissue is impaired, antibiotics cannot penetrate into the infected tissue. As a result, surgery to remove the dead, damaged, or infected tissue is the cornerstone of treatment for necrotizing fasciitis.[1][2] In addition, early surgical treatment may minimize tissue loss, eliminating the need for amputation of the infected extremity.[3] The choice of antibiotics will likely depend on the particular bacteria involved. Supplemental oxygen, fluids, and medicines may be needed to raise the blood pressure.[4] Hyperbaric oxygen therapy and intravenous immunoglobulin may also be considered, but their use in patients with NF is considered controversial by some.[1][4]
Last updated: 4/13/2016

References
  1. Sarani, Babak. Necrotizing Fasciitis. National Organization of Rare Disorders (NORD). 2015; http://rarediseases.org/rare-diseases/necrotizing-fasciitis/. Accessed 4/12/2016.
  2. Necrotizing Fasciitis: A Rare Disease, Especially for the Healthy. Centers for Disease Control and Prevention (CDC). April 17, 2015; http://www.cdc.gov/features/necrotizingfasciitis/. Accessed 4/12/2016.
  3. Edlich, Richard. Necrotizing Fasciitis. Medscape Reference. July 9, 2015; http://emedicine.medscape.com/article/2051157-overview. Accessed 4/13/2016.
  4. Necrotizing fasciitis. DermNet New Zealand Trust. March 4, 2016; http://www.dermnetnz.org/bacterial/necrotising-fasciitis.html. Accessed 4/12/2016.


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Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Necrotizing fasciitis. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.