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Diseases

Genetic and Rare Diseases Information Center (GARD)

Diffuse idiopathic skeletal hyperostosis

*

* Not a rare disease

Other Names for this Disease
  • Ankylosing vertebral hyperostosis with tylosis
  • DISH
  • DISH Forestier's disease
  • Forestier disease
  • Forestier-Rotes disease
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Cause

Newline Maker

What causes diffuse idiopathic skeletal hyperostosis ?

The exact underlying cause of diffuse idiopathic skeletal hyperostosis (DISH) is poorly understood. However, several factors have been associated with an increased risk of developing the condition. For example, conditions that disturb cartilage metabolism (such as diabetes mellitus, acromegaly, or certain inherited connective tissue disorders) may lead to DISH. Long-term use of medications called retinoids (such as isotretinoin) can increase the risk for DISH. Age (being older than age 50) and sex (being male) may also play a role.[1][2]
Last updated: 5/11/2015

References
  1. Simon M Helfgott, MD. Diffuse idiopathic skeletal hyperostosis (DISH). UpToDate. December 2013; Accessed 5/11/2015.
  2. Diffuse idiopathic skeletal hyperostosis (DISH). Mayo Foundation for Medical Education and Research. November 2, 2012; http://www.mayoclinic.com/print/diffuse-idiopathic-skeletal-hyperostosis/DS00740/DSECTION=all&METHOD=print. Accessed 11/17/2013.


Other Names for this Disease
  • Ankylosing vertebral hyperostosis with tylosis
  • DISH
  • DISH Forestier's disease
  • Forestier disease
  • Forestier-Rotes disease
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.