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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Diffuse idiopathic skeletal hyperostosis

*

* Not a rare disease

Other Names for this Disease
  • Ankylosing vertebral hyperostosis with tylosis
  • DISH
  • DISH Forestier's disease
  • Forestier disease
  • Forestier-Rotes disease
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Symptoms

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What are the signs and symptoms of Diffuse idiopathic skeletal hyperostosis?

Many people affected by diffuse idiopathic skeletal hyperostosis (DISH) have no signs or symptoms of the condition. When present, symptoms vary but many include:[1][2][3]
  • Stiffness which is most noticeable in the morning
  • Pain when pressure is applied to the affected area
  • Loss of range of motion
  • Difficulty swallowing or a hoarse voice
  • Tingling, numbness, and/or weakness in the legs

The upper portion of the back (thoracic spine) is the most commonly affected site; however, people with DISH may also experience symptoms in other places such as the heels, ankles, knees, hips, shoulders, elbows, and/or hands.[1][2][3]
Last updated: 5/11/2015

The Human Phenotype Ontology provides the following list of signs and symptoms for Diffuse idiopathic skeletal hyperostosis. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the definitions for these medical terms.

Signs and Symptoms Approximate number of patients (when available)
Osteoarthritis 90%
Obesity 50%
Palmoplantar keratoderma 50%
Autosomal dominant inheritance -
Punctate palmar and solar hyperkeratosis -
Vertebral hyperostosis -

Last updated: 7/1/2015

The Human Phenotype Ontology (HPO) has collected information on how often a sign or symptom occurs in a condition. Much of this information comes from Orphanet, a European rare disease database. The frequency of a sign or symptom is usually listed as a rough estimate of the percentage of patients who have that feature.

The frequency may also be listed as a fraction. The first number of the fraction is how many people had the symptom, and the second number is the total number of people who were examined in one study. For example, a frequency of 25/25 means that in a study of 25 people all patients were found to have that symptom. Because these frequencies are based on a specific study, the fractions may be different if another group of patients are examined.

Sometimes, no information on frequency is available. In these cases, the sign or symptom may be rare or common.


References
  1. Diffuse idiopathic skeletal hyperostosis (DISH). Mayo Foundation for Medical Education and Research. November 2, 2012; http://www.mayoclinic.com/print/diffuse-idiopathic-skeletal-hyperostosis/DS00740/DSECTION=all&METHOD=print. Accessed 11/17/2013.
  2. Bruce M Rothschild, MD. Diffuse Idiopathic Skeletal Hyperostosis. Medscape Reference. March 2015; http://emedicine.medscape.com/article/1258514-overview.
  3. Simon M Helfgott, MD. Diffuse idiopathic skeletal hyperostosis (DISH). UpToDate. December 2013; Accessed 5/11/2015.


Other Names for this Disease
  • Ankylosing vertebral hyperostosis with tylosis
  • DISH
  • DISH Forestier's disease
  • Forestier disease
  • Forestier-Rotes disease
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.