Other Names for this Disease
- Autoerythrocyte sensitization
- Autoerythrocyte sensitization purpura
- HCHWA, Piedmont type
- Hereditary cerebral hemorrhage with amyloidosis, Piedmont type
- Painful bruising syndrome
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Tests & Diagnosis
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There are no specific tests that can confirm the diagnosis of Gardner-Diamond syndrome. The diagnosis may be considered when an individual has the signs and symptoms of the condition but all other causes of bleeding have been ruled out. A positive intracutaneous test with autoerythrocytes may also be helpful in making a diagnosis. This is essentially an injection of autoerythrocytes into the skin to determine if an allergic reaction is present. Additionally, a detailed psychiatric evaluation is extremely important when a diagnosis of this syndrome is suspected because an abnormal psychiatric history is typically present in affected individuals.
Last updated: 9/14/2011
- OL Ivanov, AN Lvov, AV Michenko, J Künzel, P Mayser, U Gieler. Autoerythrocyte sensitization syndrome (Gardner–Diamond syndrome): review of the literature. Journal of the European Academy of Dermatology and Venereology. 2009; 23(5):499-504.
- Benjamin P Geisler, Bruce J Dezube. Psychogenic purpura (Gardner-Diamond syndrome). UpToDate. January 19, 2011; http://www.uptodate.com/contents/psychogenic-purpura-gardner-diamond-syndrome. Accessed 9/12/2011.