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Diseases

Genetic and Rare Diseases Information Center (GARD)

Pemphigoid gestationis


Other Names for this Disease
  • Gestational pemphigoid
  • Herpes gestationis
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Treatment

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How might pemphigoid gestationis be treated?

The goals of treatment for women with pemphigoid gestationis (PG) are to relieve itching, prevent blister formation, and treat any secondary infections.[1][2] Treatment may depend on the severity in each person, and the risks and benefits of therapies need to be considered for both the mother and the fetus.[1] In most cases, PG resolves spontaneously (on its own) within days after delivery, so treatment can usually be tapered off and stopped.[2]

Topical corticosteroids may be used in milder cases, while oral corticosteroids are needed in more severe cases. Oral antihistamines may also be used to relieve itching. Intravenous immunoglobulin (IVIG) has also been reported to be effective. Certain immunosuppressive medications may also be effective, but their safety during pregnancy and/or breastfeeding must be considered.[2]
Last updated: 5/3/2016

References
  1. Anatoli Freiman. Pemphigoid Gestationis. Medscape Reference. August 17, 2015; http://emedicine.medscape.com/article/1063499-overview.
  2. Vanessa Ngan. Pemphigoid gestationis. DermNet NZ. April 25, 2016; http://www.dermnetnz.org/immune/pemphigoid-gestationis.html.


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Other Names for this Disease
  • Gestational pemphigoid
  • Herpes gestationis
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.