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Diseases

Genetic and Rare Diseases Information Center (GARD)

Pemphigoid gestationis


Other Names for this Disease
  • Gestational pemphigoid
  • Herpes gestationis
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Treatment

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What treatment is available for pemphigoid gestationis?

Patients with HG typically respond well to low-dose treatment with oral corticosteroids like prednisone. In more resistant cases, higher doses or oral corticosteroids might be needed. Up to about 75 percent of patients experience a spontaneous resolution or improvement during the late third trimester, and treatment might be discontinued. Since post-delivery flare-ups of HG are common, some individuals who had experienced improvement may require an increase in corticosteroids doses in anticipation. For more difficult-to-manage cases treatment may includes topical corticosteroids, oral antihistamines, and immunosuppressants.[1][2]
Last updated: 8/11/2010

References
  1. Doiron P, Pratt M. Antepartum intravenous immunoglobulin therapy in refractory pemphigoid gestationis: case report and literature review. J Cutan Med Surg. 2010 Jul-Aug;
  2. Specific Dermatoses of Pregnancy. In: Gabbe SG, Niebyl JR, Simpson JL. Gabbe: Obstetrics: Normal and Problem Pregnancies, 5th ed. Philadelphia: Churchill Livingstone Elsevier; 2007;


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Other Names for this Disease
  • Gestational pemphigoid
  • Herpes gestationis
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.