Gianotti Crosti syndrome
Other Names for this Disease
- Acrodermatitis, infantile lichenoid
- Acrodermatitis, papular infantile
- Crosti-gianotti syndrome
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papular rash with blisters on the skin of the legs, buttocks, and arms. It typically affects children between 9 months and 9 years of age. Skin lesions typically last at least 10 days and often last for several weeks. The lesions are usually preceded by an underlying infection (usually a virus), which may cause associated symptoms such as low-grade fever, sore throat, or symptoms of an upper respiratory infection. When GCS is associated with hepatitis B, Epstein-Barr, or cytomegalovirus (CMV) infection, acute hepatitis may also occur. GCS is thought to be a hypersensitive response to the underlying infection. While in many countries the underlying cause is hepatitis B, this is rarely the cause in North America. GCS typically does not require treatment and goes away on its own within 1 to 3 months. In some cases, a mild topical steroid cream may be prescribed to relieve itching.Gianotti Crosti syndrome (GCS) is a rare childhood skin condition characterized by a
Last updated: 9/26/2015
- Gianotti Crosti Syndrome. NORD. 2009; http://rarediseases.org/rare-diseases/gianotti-crosti-syndrome/.
- Sören A Craig-Müller. Gianotti-Crosti Syndrome. Medscape Reference. August 1, 2014; http://emedicine.medscape.com/article/911275-overview.
- Amanda Oakley. Infantile papular acrodermatitis. DermnetNZ. September 19, 2015; http://dermnetnz.org/viral/gianotti-crosti.html.
- DermNet NZ is an online resource about skin diseases developed by the New Zealand Dermatological Society Incorporated. DermNet NZ provides information about this condition.
- MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
- The National Organization for Rare Disorders (NORD) has a report for patients and families about this condition. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.