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Genetic and Rare Diseases Information Center (GARD)

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Gilbert syndrome

*

* Not a rare disease

Other Names for this Disease
  • Cholemia, familial
  • Gilbert's disease
  • Hyperbilirubinemia Arias type
  • Hyperbilirubinemia type 1
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Gilbert syndrome is a common, mild liver disorder in which the liver doesn't properly process bilirubin, a substance produced by the breakdown of red blood cells. Gilbert syndrome typically doesn't require treatment or pose serious complications. In fact, Gilbert syndrome is usually not considered a disease because of its benign nature. Many individuals find out they have the disorder by accident, when they have a blood test that shows elevated bilirubin levels. More males than females have been diagnosed with Gilbert syndrome.[1] This condition is caused by mutations in the UGT1A1 gene and is inherited in an autosomal recessive pattern.[2]
Last updated: 5/2/2011

References

  1. Gilbert Syndrome. MayoClinic.com. June 22, 2012; http://www.mayoclinic.com/print/gilberts-syndrome/DS00743/DSECTION=all&METHOD=print. Accessed 5/4/2015.
  2. Gilbert Syndrome. Online Mendelian Inheritance of Man (OMIM). January 12, 2012; http://www.ncbi.nlm.nih.gov/omim/143500. Accessed 5/4/2015.
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Basic Information

  • Genetics Home Reference (GHR) contains information on Gilbert syndrome. This website is maintained by the National Library of Medicine.
  • MayoClinic.com has an information page on Gilbert syndrome. Click on the link to view this page.
  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.

In Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs.  Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Gilbert syndrome. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Cholemia, familial
  • Gilbert's disease
  • Hyperbilirubinemia Arias type
  • Hyperbilirubinemia type 1
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.