Focal segmental glomerulosclerosis
Other Names for this Disease
- Glomerulosclerosis, focal
- Segmental glomerulosclerosis
- Focal sclerosis with hyalinosis
- Familial idiopathic nephrotic syndrome
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 FSGS may cause non-specific signs and symptoms, including protein in the urine, elevated levels of creatinine, and swelling. In many cases the cause of FSGS can not be determined. Some cases are thought to be associated with congenital kidney defects, urine backing up into the kidneys, obesity, obstructive sleep apnea, sickle cell anemia, or viruses (e.g., HIV). The goal of treatment is to control symptoms and prevent chronic kidney failure. Even with treatment, many people with FSGS progress to kidney failure within 5 to 20 years.Focal segmental glomerulosclerosis (FSGS) is a type of kidney disorder. It is characterized by scar tissue that forms in some of the glomeruli in the kidney.
Last updated: 11/4/2015
- Focal segmental glomerulosclerosis. MedlinePlus. October 21, 2015; http://www.nlm.nih.gov/medlineplus/ency/article/000478.htm. Accessed 11/4/2015.
- Glomerular diseases. National Kidney & Urologic Diseases Information Clearinghouse. April 2, 2014; http://kidney.niddk.nih.gov/kudiseases/pubs/glomerular/. Accessed 11/4/2015.
- Focal segmental glomerulosclerosis (FSGS). UNC Kidney Center Web site. http://unckidneycenter.org/kidney-health-library/glomerular-disease/focal-segmental-glomerulosclerosis-fsgs. Accessed 11/4/2015.
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- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- The Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
- Online Mendelian Inheritance in Man (OMIM) lists the subtypes and associated genes for Focal segmental glomerulosclerosis in a table called Phenotypic Series. Each entry in OMIM includes a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Focal segmental glomerulosclerosis. Click on the link to view a sample search on this topic.