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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Glutaric acidemia type I


Other Names for this Disease
  • GA 1
  • GA1
  • GCDHD
  • Glutaric acidemia 1
  • Glutaric acidemia type 1
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Inheritance

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How is glutaric acidemia type I inherited?

Glutaric acidemia type I is inherited in an autosomal recessive manner.[1] This means that both copies of the responsible gene in each cell must have mutations for a person to be affected. The parents of a person with an autosomal recessive condition typically each carry one mutated copy of the gene and are referred to as carriers. Carriers of an autosomal recessive condition typically are unaffected and have no signs or symptoms.

When two carrier parents have children, each child has a 25% (1 in 4) chance to be affected, a 50% (1 in 2) chance to be an unaffected carrier like each parent, and a 25% chance to be unaffected and not be a carrier.
Last updated: 4/29/2015

References
  1. Glutaric acidemia type I. Genetics Home Reference (GHR). March, 2007; http://www.ghr.nlm.nih.gov/condition/glutaric-acidemia-type-i.


Other Names for this Disease
  • GA 1
  • GA1
  • GCDHD
  • Glutaric acidemia 1
  • Glutaric acidemia type 1
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.