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Diseases

Genetic and Rare Diseases Information Center (GARD)

Granulomatous rosacea


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Treatment

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How might granulomatous rosacea be treated?

As with other types or rosacea, patients with granulomatous rosacea are advised to avoid known exacerbating factors such as hot drinks, alcohol, and extremes of temperature. In  addition, they should be encouraged to use a noncomedogenic high-factor sunscreen when exposed to sunlight and wind.[1] Treatment of granulomatous rosacea is not different from classical rosacea and tetracycline, doxycyclineerythromycin or minocycline are usually effective.[1][2] In addition, topical metronidazole may be helpful for mild disease and in addition to systemic therapy. Topical keratolytics such as benzoyl peroxide and azelaic acid offer limited symptomatic control of inflammatory pustules. Isotretinoin (Accutane) may be helpful for recalcitrant (hard to treat) disease, but recurrence is common. Long-term, low-dose isotretinoin therapy may be suitable for some patients. Dapsone has a pharmacological double function as both an antibiotic and an anti-inflammatory drug. The value of dapsone in granulomatous rosacea, however, has not yet been established by controlled studies. Permanent telangiectasia may be treated by electrosurgery or by pulsed dye laser.[1] 

More in-depth information about the treatment of rosacea, including granulomatous rosacea, can be found on the eMedicine web page.  

Last updated: 4/26/2010

References
  1. Khikhar O, Khachemoune A. Dermatology Online Journal. 2004; http://dermatology.cdlib.org/101/case_reports/rosacea/khachemoune.html. Accessed 4/26/2010.
  2. Kaur S, Kanwar AJ, Thami GP, Mohan H, Arya SK. 2003; http://www.ijdvl.com/article.asp?issn=0378-6323;year=2003;volume=69;issue=7;spage=58;epage=60;aulast=Kaur. Accessed 4/26/2010.


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