Other Names for this Disease
- Acute autoimmune peripheral neuropathy
- Acute immune-mediated polyneuropathy
- Acute inflammatory demyelinating polyneuropathy
- Acute inflammatory demyelinating polyradiculoneuropathy
peripheral nervous system. Symptoms include muscle weakness, numbness, and tingling sensations, which can increase in intensity until the muscles cannot be used at all. Usually Guillain-Barré syndrome occurs a few days or weeks after symptoms of a viral infection. Occasionally, surgery or vaccinations will trigger the syndrome. It remains unclear why only some people develop Guillain-Barré syndrome but there may be a genetic predisposition in some cases. Diagnosed patients should be admitted to a hospital for early treatment. There is no cure for Guillain-Barré syndrome, but treatments such as plasma exchange (plasmapheresis) and high dose immunoglobulins may reduce the severity and duration of symptoms. Recovery can take as little as a few days to as long as a few years. About 30% of those with Guillain-Barré syndrome have residual weakness. A small number may suffer a relapse many years after the initial attack.Guillain-Barré syndrome is a rare disorder in which the body's immune system attacks part of the
Last updated: 1/16/2016
- Guillain-Barré Syndrome Fact Sheet. National Institute of Neurological Disorders and Stroke Web site. April 29, 2015; http://www.ninds.nih.gov/disorders/gbs/detail_gbs.htm.
- Guillain-Barre syndrome, familial. OMIM database. April 8, 2009; http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=139393.
- Andary M & cols. Guillain-Barre Syndrome. Medscape Reference. July 1, 2015; http://emedicine.medscape.com/article/315632-overview#aw2aab6b2b5.
- Genetics Home Reference (GHR) contains information on Guillain-Barre syndrome. This website is maintained by the National Library of Medicine.
- MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
- The Merck Manuals Online Medical Library provides information on this condition for patients and caregivers.
- The National Institute of Neurological Disorders and Stroke (NINDS) collects and disseminates research information related to neurological disorders. Click on the link to view information on this topic.
- The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Guillain-Barre syndrome. Click on the link to view a sample search on this topic.