Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Guillain-Barre syndrome


Other Names for this Disease
  • Acute autoimmune peripheral neuropathy
  • GBS
  • Acute immune-mediated polyneuropathy
  • Acute inflammatory demyelinating polyneuropathy
  • Acute inflammatory demyelinating polyradiculoneuropathy
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Your Question

I have just recovered from Guillian-Barre syndrome. I want to know if it will affect me again?

Our Answer

We have identified the following information that we hope you find helpful. If you still have questions, please contact us.

What is the long-term outlook for people with Guillain-Barre syndrome?

The long-term outlook (prognosis) for people with Guillain-Barre syndrome (GBS) varies considerably. About 80% of people with GBS walk independently 6 months after the diagnosis, and about 84% walk independently one year after the diagnosis. About 60% of people with GBS have full motor strength recovery at one year, but severe motor problems persist in about 14%. Five to ten percent have a prolonged course, with several months of ventilator dependency and very delayed and incomplete recovery.[1]

Within a year of diagnosis, death occurs in about 4 to 5 percent of affected people, despite intensive care. Causes of death include acute respiratory distress syndrome, sepsis, pulmonary emboli, and unexplained cardiac arrest.[1]

In about 10% of people with GBS, an acute relapse occurs after initial improvement or stabilization after treatment. The risk of relapse appears to be higher in those who have had a later onset of treatment, a longer-lasting disease course, and more associated medical conditions. Recurrence of GBS is rare but has been reported in 2-5% of affected people.[2] About 2 percent go on to develop chronic inflammatory demyelinating polyradiculoneuropathy (CIDP).[1]
Last updated: 12/10/2015

References
Other Names for this Disease
  • Acute autoimmune peripheral neuropathy
  • GBS
  • Acute immune-mediated polyneuropathy
  • Acute inflammatory demyelinating polyneuropathy
  • Acute inflammatory demyelinating polyradiculoneuropathy
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.