Other Names for this Disease
- Acute autoimmune peripheral neuropathy
- Acute immune-mediated polyneuropathy
- Acute inflammatory demyelinating polyneuropathy
- Acute inflammatory demyelinating polyradiculoneuropathy
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peripheral nervous system. Symptoms include muscle weakness, numbness, and tingling sensations, which can increase in intensity until the muscles cannot be used at all. Usually Guillain-Barré syndrome occurs a few days or weeks after symptoms of a viral infection. Occasionally, surgery or vaccinations will trigger the syndrome. It remains unclear why only some people develop Guillain-Barré syndrome but there may be a genetic predisposition in some cases. Diagnosed patients should be admitted to a hospital for early treatment. There is no cure for Guillain-Barré syndrome, but treatments such as plasma exchange (plasmapheresis) and high dose immunoglobulins may reduce the severity and duration of symptoms. Recovery can take as little as a few days to as long as a few years. About 30% of those with Guillain-Barré syndrome have residual weakness. A small number may suffer a relapse many years after the initial attack.Guillain-Barré syndrome is a rare disorder in which the body's immune system attacks part of the
Last updated: 1/16/2016
- Guillain-Barré Syndrome Fact Sheet. National Institute of Neurological Disorders and Stroke Web site. April 29, 2015; http://www.ninds.nih.gov/disorders/gbs/detail_gbs.htm.
- Guillain-Barre syndrome, familial. OMIM database. April 8, 2009; http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=139393.
- Andary M & cols. Guillain-Barre Syndrome. Medscape Reference. July 1, 2015; http://emedicine.medscape.com/article/315632-overview#aw2aab6b2b5.
- Genetics Home Reference (GHR) contains information on Guillain-Barre syndrome. This website is maintained by the National Library of Medicine.
- MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
- The Merck Manuals Online Medical Library provides information on this condition for patients and caregivers.
- The National Institute of Neurological Disorders and Stroke (NINDS) collects and disseminates research information related to neurological disorders. Click on the link to view information on this topic.
- The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Guillain-Barre syndrome. Click on the link to view a sample search on this topic.