Factor XII deficiency
Other Names for this Disease
- Coagulation factor 12 deficiency
- Congenital factor XII deficiency
- Congenital Hageman factor deficiency
- F12 deficiency
- Factor 12 deficiency
 Factor XII deficiency is caused by mutations in the F12 gene. It is inherited in an autosomal recessive manner.Factor XII deficiency is an inherited disorder that affects a protein (factor XII) involved in blood clotting. While a lack of factor XII does not cause affected individuals to bleed abnormally, the blood takes longer than normal to clot in a test tube. The condition is usually discovered when prolonged clotting is noticed in the process of running other laboratory tests.
Last updated: 6/24/2011
- Dugdale DC, Chen YB. Factor XII (Hageman factor) deficiency. MedlinePlus. 2011; http://www.nlm.nih.gov/medlineplus/ency/article/000545.htm. Accessed 6/24/2011.
- Factor XII Deficiency. Online Mendelian Inheritance in Man (OMIM). 2010; http://www.ncbi.nlm.nih.gov/omim/234000. Accessed 6/24/2011.
- MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
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- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
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