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Diseases

Genetic and Rare Diseases Information Center (GARD)

Essential thrombocythemia


Other Names for this Disease
  • Primary thrombocythemia
  • Hemorrhagic thrombocythemia
  • Essential thrombocytosis
  • Idiopathic thrombocythemia
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Essential thrombocythemia belongs to a group of conditions called myeloproliferative disorders. Myeloproliferative disorders cause platelets, white blood cells and red blood cells to grow abnormally in the bone marrow (the soft tissue inside the hollow part of bones that helps form blood cells). In essential thrombocythemia, the body produces too many platelet cells. The signs and symptoms vary from person to person, with up to two-thirds of patients not having any symptoms when the platelet cell count first increases. Signs and symptoms may include significant increased production of megakaryocyte (a cell in the bone marrow that is responsible for making platelets), enlargement of the spleen (splenomegaly), and bleeding and/or clotting episodes.[1][2]
Last updated: 12/30/2015

References

  1. Primary thrombocythemia. MedlinePlus Medical Encyclopedia. 2/13/2015; http://www.nlm.nih.gov/medlineplus/ency/article/000543.htm. Accessed 12/30/2015.
  2. Essential Thrombocythemia. National Cancer Institute. June 26, 2015; http://www.cancer.gov/types/myeloproliferative/patient/chronic-treatment-pdq#link/stoc_h2_4. Accessed 7/8/2015.
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Basic Information

  • Genetics Home Reference (GHR) contains information on Essential thrombocythemia. This website is maintained by the National Library of Medicine.
  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The Merck Manuals Online Medical Library provides information on this condition for patients and caregivers. 
  • The CMPD Education Foundation provides online information on myeloproliferative disorders (MPD). Click on the link to view the resource.
  • The National Cancer Institute provides the most current information on cancer for patients, health professionals, and the general public.
  • The National Heart, Lung, and Blood Institute (NHLBI) has information on this topic. NHLBI is part of the National Institutes of Health and supports research, training, and education for the prevention and treatment of heart, lung, and blood diseases.
  • The National Organization for Rare Disorders (NORD) has a report for patients and families about this condition. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.

In Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Essential thrombocythemia. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Primary thrombocythemia
  • Hemorrhagic thrombocythemia
  • Essential thrombocytosis
  • Idiopathic thrombocythemia
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.