Thyroid cancer, anaplastic
Other Names for this Disease
- Anaplastic thyroid cancer
- Thyroid carcinoma, anaplastic
- Anaplastic thyroid carcinoma
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 Most cases of anaplastic thyroid cancer are diagnosed in the sixth to seventh decade of life. Women are more likely to be affected than men. ATC generally occurs in individuals with a history of goiter or thyroid cancer. A history of head and neck radiation or exposure to radioactive materials may also increase the risk for ATC. Patients with ATC generally present with a rapidly-growing neck mass which may cause trouble swallowing (dysphagia), coughing, neck pain, and trouble breathing (dyspnea). Metastasis is present in more than half of individuals at the time of diagnosis. Patients with metastases may also present with bone pain, lymph node enlargement, weakness, and neurological deficits. Treatment of ATC is mostly palliative.Anaplastic thyroid cancer (ATC) accounts for less than 2% of all thyroid cancers and is the most aggressive type of thyroid cancer.
Last updated: 7/1/2015
- Anastasios K Konstantakos. Anaplastic Thyroid Carcinoma. Medscape. April 16, 2015; http://emedicine.medscape.com/article/283165-overview. Accessed 7/1/2015.
- Thyroid cancer: Anaplastic Thyroid Cancer (ATC). The American Association of Endocrine Surgeons. http://endocrinediseases.org/thyroid/cancer_anaplastic.shtml#top. Accessed 7/1/2015.
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- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Thyroid cancer, anaplastic. Click on the link to view a sample search on this topic.