Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Thyroid cancer, anaplastic


Other Names for this Disease
  • Anaplastic thyroid cancer
  • Anaplastic thyroid carcinoma
  • Thyroid carcinoma, anaplastic
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Anaplastic thyroid cancer (ATC) accounts for less than 2% of all thyroid cancers and is the most aggressive type of thyroid cancer.[1] Most cases of anaplastic thyroid cancer are diagnosed in the sixth to seventh decade of life. Women are more likely to be affected than men.[1] ATC generally occurs in individuals with a history of goiter or thyroid cancer.[1] A history of head and neck radiation or exposure to radioactive materials may also increase the risk for ATC.[2] Patients with ATC generally present with a rapidly-growing neck mass which may cause trouble swallowing (dysphagia), coughing, neck pain, and trouble breathing (dyspnea).[1] Metastasis is present in more than half of individuals at the time of diagnosis. Patients with metastases may also present with bone pain, lymph node enlargement, weakness, and neurological deficits.[1] Treatment of ATC is mostly palliative.[1]
Last updated: 7/1/2015

References

  1. Anastasios K Konstantakos. Anaplastic Thyroid Carcinoma. Medscape. April 16, 2015; http://emedicine.medscape.com/article/283165-overview. Accessed 7/1/2015.
  2. Thyroid cancer: Anaplastic Thyroid Cancer (ATC). The American Association of Endocrine Surgeons. http://endocrinediseases.org/thyroid/cancer_anaplastic.shtml#top. Accessed 7/1/2015.
GARD Video Tutorials
GARD Video Tutorials
Learn how to find information on treatment, research, specialists, and more.
Contact GARD
Contact GARD
Contact a GARD Information Specialist with your questions about this condition.
On this page

In Depth Information

  • PubMed is a searchable database of medical literature and lists journal articles that discuss Thyroid cancer, anaplastic. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Anaplastic thyroid cancer
  • Anaplastic thyroid carcinoma
  • Thyroid carcinoma, anaplastic
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.