Mucopolysaccharidosis type II
Other Names for this Disease
- MPS II
- Attenuated MPS (subtype; formerly known as mild MPS II)
- Severe MPS II
- Hunter syndrome
- Iduronate 2-sulfatase deficiency
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MPS II is inherited in an X-linked recessive pattern, which means that this conditions occurs almost exclusively in males. Females are generally unaffected carriers of this condition. In a family with more than one affected individual, the mother of the affected males must be a carrier. When a carrier female has a child, there is a 25% (1 in 4) chance that she will have a affected son.
Last updated: 9/20/2013
- Martin RA. Mucopolysaccharidosis Type II. Gene Reviews. March 26, 2015; http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gene&part=hunter.