Other Names for this Disease
- Ichthyosis simplex
- Common ichthyosis
- Fish scale disease
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Ichthyosis vulgaris is caused by a genetic mutation. The mutated gene causes an abnormality in the normal lifecycle of skin. Whilst in most people, the growth, dying and shedding of skin happens unnoticed, people with ichthyosis reproduce new skin cells at a rate faster than they can shed it, or reproduce at a normal rate but the rate of shedding is too slow. Either way there is a build up of dry scaly skin. The mutated gene in ichthyosis vulgaris is found on chromosome 1q21 and is related to a protein called filaggrin. To learn more about the protein filaggrin please click here.
Last updated: 10/18/2013
- Ichthyosis. DermNet NZ. January 2013; http://www.dermnetnz.org/scaly/ichthyosis.html. Accessed 1/24/2013.