Other Names for this Disease
- Intestinal pseudoobstruction
- Hollow visceral myopathy
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failure to thrive; and other symptoms. It may be classified as neuropathic (from lack of nerve function) or myopathic (from lack of muscle function), depending on the source of the abnormality. The condition is sometimes inherited (in an X-linked recessive or autosomal dominant manner) and may be caused by mutations in the FLNA gene; it may also be acquired after certain illnesses. The goal of treatment is to provide relief from symptoms and ensure that nutritional support is adequate.Intestinal pseudo-obstruction is a digestive disorder in which the intestinal walls are unable to contract normally (called hypomotility); the condition resembles a true obstruction, but no actual blockage exists. Signs and symptoms may include abdominal pain; vomiting; diarrhea; constipation; malabsorption of nutrients leading to weight loss and/or
Last updated: 4/1/2015
- Soffer EE. Chronic Intestinal Pseudo-obstruction. NORD. 2012; http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/452/viewAbstract. Accessed 4/1/2015.
- Intestinal pseudo-obstruction. Genetics Home Reference. October 2010; http://ghr.nlm.nih.gov/condition/intestinal-pseudo-obstruction. Accessed 5/10/2011.
- Genetics Home Reference (GHR) contains information on Intestinal pseudo-obstruction. This website is maintained by the National Library of Medicine.
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- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
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