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Diseases

Genetic and Rare Diseases Information Center (GARD)

Isaacs' syndrome


Other Names for this Disease
  • Neuromyotonia
  • Isaac's-Merten's syndrome
  • Continuous muscle fiber activity syndrome
  • Quantal squander syndrome
  • Acquired neuromyotonia
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Treatment

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How might Isaacs' syndrome be treated?

The treatment of Isaacs' syndrome is based on the signs and symptoms present in each person. For example, anticonvulsant medications such as phenytoin and carbamazepine may be prescribed to relieve stiffness, muscle spasms, and pain. Plasma exchange may provide short-term relief for people with some forms of acquired Isaacs' syndrome. Plasma exchange is a method by which whole blood is removed from the body and processed so that the red and white blood cells are separated from the plasma (liquid portion of the blood). The blood cells are then returned to the patient without the plasma, which the body quickly replaces. If there is no response or poor response to plasma exchange, some studies suggest that intravenous infusions of immunoglobulins (IvIg therapy) may be beneficial.[1][2]
Last updated: 9/17/2015

References
  1. NINDS Isaac's Syndrome Information Page. National Institute of Neurological Disorders and Stroke (NINDS). September 2015; http://www.ninds.nih.gov/disorders/isaacs_syndrome/isaacs_syndrome.htm.
  2. Ahmed A, Simmons Z. Isaacs syndrome: A review. Muscle Nerve. July 2015; 52(1):5-12.


GARD Video Tutorial

  • Finding Treatment Information - A video developed by GARD Information Specialists that explains how you can find information about treatment for a rare disease.

    Finding Treatment Information

Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Isaacs' syndrome. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
Other Names for this Disease
  • Neuromyotonia
  • Isaac's-Merten's syndrome
  • Continuous muscle fiber activity syndrome
  • Quantal squander syndrome
  • Acquired neuromyotonia
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.