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Diseases

Genetic and Rare Diseases Information Center (GARD)

Juvenile dermatomyositis


Other Names for this Disease
  • JDM
  • Juvenile myositis
  • JPM
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Juvenile dermatomyositis has some similarities to adult dermatomyositis and polymyositis. It typically affects children ages 2 to 15 years, with symptoms that include weakness of the muscles close to the trunk of the body, inflammation, edema, muscle pain, fatigue, skin rashes, abdominal pain, fever, and contractures. Children with juvenile dermatomyositis may have difficulty swallowing and breathing, and the heart may also be affected.  About 20 to 30 percent of children with juvenile dermatomyositis develop calcium deposits in the soft tissue. Affected children may not show higher than normal levels of the muscle enzyme creatine kinase in their blood but have higher than normal levels of other muscle enzymes.[1] Treatment is aimed at addressing the individual symptoms of each patient. This may involve a combination of medications, physical therapy and supplements.[2]
Last updated: 7/25/2016

References

  1. Inflammatory Myopathies Fact Sheet. National Institute of Neurological Disorders and Stroke (NINDS). July 27, 2015; http://www.ninds.nih.gov/disorders/inflammatory_myopathies/detail_inflammatory_myopathies.htm.
  2. Myositis: Treatment. The Myositis Association. March 2015; http://www.myositis.org/learn-about-myositis/treatment.
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Basic Information

  • MedlinePlus, the National Library of Medicine Web site designed to help you research your health questions, provides general information on myositis. Click on the link to view this information.
  • The National Institute of Neurological Disorders and Stroke (NINDS) collects and disseminates research information related to neurological disorders. Click on the link to view information on this topic.
  • The Myositis Association provides basic information on juvenile myositis.

In Depth Information

  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Juvenile dermatomyositis. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • JDM
  • Juvenile myositis
  • JPM
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.