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Diseases

Genetic and Rare Diseases Information Center (GARD)

Kawasaki disease


Other Names for this Disease
  • Mucocutaneous lymph node syndrome
  • Kawasaki syndrome
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

Kawasaki disease is a condition that involves inflammation of the blood vessels. It is typically diagnosed in young children, but older children and adults can also develop this condition. Kawasaki disease begins with a fever that lasts at least 5 days. Other classic symptoms may include red eyes, lips, and mouth; rash; swollen and red hands and feet; and swollen lymph nodes.[1] Sometimes the condition affects the coronary arteries (which carry oxygen-rich blood to the heart). This can lead to serious heart problems. Kawasaki disease occurs most often in people of Asian and Pacific Island descent.[2] The cause of Kawasaki disease is unknown.[1][2] An infection along with genetic factors may be involved.[2] Treatment includes intravenous gamma globulin and high doses of aspirin in a hospital setting.[1][2]  
Last updated: 2/3/2016

References

  1. Starkebaum GA. Kawasaki disease. MedlinePlus. April 20, 2013; http://www.nlm.nih.gov/medlineplus/ency/article/000989.htm.
  2. Kawasaki disease. National Heart Lung and Blood Institute Web site. September 20, 2011; http://www.nhlbi.nih.gov/health/health-topics/topics/kd/.
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Basic Information

  • The Centers for Disease Control and Prevention (CDC) provide more information on reporting cases of Kawasaki syndrome.  Click on the CDC link to view this information.

    National Center for Zoonotic, Vector-Borne, Enteric Diseases (NCZVED)
    1600 Clifton Road, NE
    MS D-76
    Atlanta, GA 30329-4018
  • You can obtain information on this topic from the Centers for Disease Control and Prevention (CDC). The CDC is recognized as the lead federal agency for developing and applying disease prevention and control, environmental health, and health promotion and education activities designed to improve the health of the people of the United States.
  • Genetics Home Reference (GHR) contains information on Kawasaki disease. This website is maintained by the National Library of Medicine.
  • The Vasculitis Foundation offers information on Kawasaki disease to assist patients, family members, and medical professionals in learning more about the condition.
  • KidsHealth created by The Nemours Foundation's Center for Children's Health Media provides information in both English and Spanish about this condition. Click on the link to access the information page on Kawasaki disease.
  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The National Heart, Lung, and Blood Institute (NHLBI) has information on this topic. NHLBI is part of the National Institutes of Health and supports research, training, and education for the prevention and treatment of heart, lung, and blood diseases.
  • The National Organization for Rare Disorders (NORD) has a report for patients and families about this condition. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.

In Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • MeSH® (Medical Subject Headings) is a terminology tool used by the National Library of Medicine. Click on the link to view information on this topic.
  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Kawasaki disease. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Mucocutaneous lymph node syndrome
  • Kawasaki syndrome
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.