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Diseases

Genetic and Rare Diseases Information Center (GARD)

Kawasaki syndrome


Other Names for this Disease
  • Kawasaki disease
  • Mucocutaneous lymph node syndrome
Related Diseases
  • Secondary glomerular disease
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Treatment

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How might Kawasaki disease be treated?

Intravenous gamma globulin is the standard treatment for Kawasaki disease and is administered in high doses. Children with Kawasaki disease usually greatly improve within 24 hours of treatment with IV gamma globulin. Aspirin is often given in combination with the IV gamma globulin as part of the treatment plan. [1]

We found limited information on the management of Kawasaki disease specifically in adults, however you may find the following articles to be helpful:

Dauphin C. et al., Kawasaki disease is also a disease of adults: report of six cases. Arch Mal Coeur Vaiss [serial online]. 2007;100(5):439-447.

Sève P, Stankovic K, Smail A, Durand DV, Marchand G, and Broussolle C. Adult Kawasaki disease: report of two cases and literature review. Semin Arthritis Rheum. 2005;34(6):785-792.

Sève P, Bui-Xuan C, Charhon A, and Broussolle C. Adult Kawasaki disease. Rev Med Interne [serial online]. 2003;24(9):577-584.

In the article listed above by Dauphin C. et al. the authors describe that of the five adult patients with Kawasaki disease who were treated, all progressed favorably after a course of immunoglobulins.  In addition, in the article by Sève P. et al., the authors comment that 'although adult KD often was diagnosed after the acute phase, when a significant beneficial effect from gammaglobulin infusion could not be expected, this treatment did appear to shorten the course of the disease.'
Last updated: 3/3/2010

References
  1. Starkebaum GA. Kawasaki disease. MedlinePlus. April 20, 2013; http://www.nlm.nih.gov/medlineplus/ency/article/000989.htm.
  2. Dauphin C. et al.,. Kawasaki disease is also a disease of adults: report of six cases. Arch Mal Coeur Vaiss . 2007; 100(5):439-447.


GARD Video Tutorial

  • Finding Treatment Information - A video developed by GARD Information Specialists that explains how you can find information about treatment for a rare disease.

    Finding Treatment Information

Management Guidelines

Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Kawasaki syndrome. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
  • The Research Portfolio Online Reporting Tool (RePORT) provides access to reports, data, and analyses of research activities at the National Institutes of Health (NIH), including information on NIH expenditures and the results of NIH-supported research. Although these projects may not conduct studies on humans, you may want to contact the investigators to learn more. To search for studies, enter the disease name in the "Text Search" box. Then click "Submit Query".
Other Names for this Disease
  • Kawasaki disease
  • Mucocutaneous lymph node syndrome
Related Diseases
  • Secondary glomerular disease
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.