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Diseases

Genetic and Rare Diseases Information Center (GARD)

Kohler disease


Other Names for this Disease
  • Kohler's Disease
  • Kohler's Disease of the Tarsal Navicular
  • Kohler's Osteochondrosis of the Tarsal Navicular
  • Navicular Osteochondrosis
  • Aseptic necrosis of the tarsal bone
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Overview

Kohler disease is a condition that affects a bone at the arch of the foot called the tarsal navicular bone. X-rays show that this bone is initially compressed and later breaks into pieces before healing and hardening back into bone. It occurs most frequently in children between the ages of 5 and 10 years. Signs and symptoms of the condition include swelling, redness and/or tenderness of the affected foot which can lead to a limp or abnormal gait (style of walking). Although the exact underlying cause of Kohler disease is unknown, some scientists suspect that it may be caused by excessive strain on the tarsal navicular bone and its associated blood vessels before the bone is completely ossified (hardened). The condition typically resolves on its own with or without treatment; however, pain relievers, rest, avoidance of weight-bearing activities, and/or casting may be recommended to help manage symptoms.[1][2]
Last updated: 2/18/2014

References

  1. Bernardo Vargas. Kohler Disease. Medscape Reference. September 2014; http://emedicine.medscape.com/article/1234753-overview.
  2. Kohler Disease. NORD. February 2008; http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/800/viewAbstract.
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Basic Information

In Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Kohler disease. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Kohler's Disease
  • Kohler's Disease of the Tarsal Navicular
  • Kohler's Osteochondrosis of the Tarsal Navicular
  • Navicular Osteochondrosis
  • Aseptic necrosis of the tarsal bone
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.