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Diseases

Genetic and Rare Diseases Information Center (GARD)

Krabbe disease


Other Names for this Disease
  • Galactocerebrosidase deficiency
  • Galactosylceramidase deficiency
  • Galactosylceramide beta-galactosidase deficiency
  • GALC deficiency
  • GCL
Related Diseases
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Prognosis

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What is the long-term outlook for people with Krabbe disease?

The long-term outlook (prognosis) for people with Krabbe disease varies by type. Infantile Krabbe disease is generally fatal before age two. However, prognosis may be better for children who receive umbilical cord blood stem cells prior to disease onset or early bone marrow transplantation.[1][2]

People with later-onset Krabbe disease generally have a milder course of the disease. However, the progression of disease and lifespan reduction can vary significantly.[1][2]
Last updated: 7/6/2015

References
  1. NINDS Krabbe Disease Information Page. National Institute of Neurological Disorders and Stroke (NINDS). June 2011; http://www.ninds.nih.gov/disorders/krabbe/krabbe.htm. Accessed 7/21/2011.
  2. David H Tegay, DO. Krabbe Disease. Medscape Reference. December 2014; http://emedicine.medscape.com/article/951722-overview.


Other Names for this Disease
  • Galactocerebrosidase deficiency
  • Galactosylceramidase deficiency
  • Galactosylceramide beta-galactosidase deficiency
  • GALC deficiency
  • GCL
Related Diseases
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.