Other Names for this Disease
- Growth hormone insensitivity syndrome
- Pituitary dwarfism II
- Growth hormone receptor deficiency
- Primary growth hormone resistance
- Primary growth hormone insensitivity
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short stature. Other signs and symptoms vary but may include reduced muscle strength and endurance; hypoglycemia in infancy; delayed puberty; short limbs (arms and legs); and obesity. It is often caused by changes (mutations) in the GHR gene and is inherited in an autosomal recessive manner. Treatment is focused on improving growth and generally includes injections of insulin-like growth factor 1 (IGF-1).Laron syndrome is a condition that occurs when the body is unable to utilize growth hormone. It is primarily characterized by
Last updated: 9/30/2015
- Laron syndrome. Genetics Home Reference. April 2015; http://ghr.nlm.nih.gov/condition/laron-syndrome.
- Alan D Rogol, MD, PhD. Growth hormone insensitivity syndromes. UpToDate. August 2015; Accessed 9/29/2015.
- Laron Z. Growth hormone insensitivity (Laron syndrome). Rev Endocr Metab Disord. December 2002; 3(4):347-355.
- Genetics Home Reference (GHR) contains information on Laron syndrome. This website is maintained by the National Library of Medicine.
- The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Laron syndrome. Click on the link to view a sample search on this topic.