Other Names for this Disease
- Autosomal dominant Larsen syndrome
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clubfoot and numerous joint dislocations at birth (affecting the hips, knees and elbows); flexible joints; and a distinctive appearance of the face, hands and feet. Larsen syndrome is inherited in an autosomal dominant manner and is caused by mutations in the FLNB gene. Management may include surgeries (especially for hip dislocation), and physiotherapy.Larsen syndrome is a condition that causes abnormal development of the bones. Signs and symptoms may include
Last updated: 3/31/2014
- Stephen Robertson. Autosomal dominant Larsen syndrome. Orphanet. July, 2013; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=503. Accessed 3/31/2014.
- Larsen syndrome. Genetics Home Reference. September, 2011; http://ghr.nlm.nih.gov/condition/larsen-syndrome. Accessed 3/31/2014.
- Genetics Home Reference (GHR) contains information on Larsen syndrome. This website is maintained by the National Library of Medicine.
- The National Organization for Rare Disorders (NORD) is a federation of more than 130 nonprofit voluntary health organizations serving people with rare disorders. Click on the link to view information on this topic.
- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Larsen syndrome. Click on the link to view a sample search on this topic.