Other Names for this Disease
- Lederhose disease
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plantar fibromatosis characterized by thickening of the foot's deep connective tissue. While many individuals with Ledderhose disease do not experience symptoms, over time the condition may progress, causing considerable pain when walking. Repeated trauma, long-term alcohol consumption, chronic liver disease, diabetes, and epilepsy have been reported in association with the development of this condition. Heredity is also a clear factor in many patients. Often, patients with Ledderhose disease also have other fibrosing conditions such as Dupuytren contracture, knuckle pads, or Peyronie disease. The exact prevalence of Ledderhose disease is unknown, with some studies stating it is rare, and others stating it is a common condition.Ledderhose disease is a type of
Last updated: 2/24/2011
- Hougeir FG, Mascaro JM. Plantar Fibromatosis. eMedicine. July 12, 2010; http://emedicine.medscape.com/article/1061903-overview. Accessed 2/17/2011.
- Ledderhose's disease. Dupuytren Society. 2011; http://www.dupuytren-online.info/morbus_ledderhose.html. Accessed 1/28/2011.
- De Souza DF, Micaelo, L, Cuzzi T, and Ramos-e-Silva M. Ledderhose Disease: An Unusual Presentation. J Clin Aesthet Dermatol. 2010; 3:45-47. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945849/?tool=pubmed. Accessed 2/17/2011.
On this page
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Ledderhose disease. Click on the link to view a sample search on this topic.