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Diseases

Genetic and Rare Diseases Information Center (GARD)

Legg-Calve-Perthes disease


Other Names for this Disease
  • Perthes disease
  • Legg-Calve-Perthes syndrome
  • LCPD
  • Osteochondritis deformans
  • Coxa plana
Related Diseases
  • Osteochondrosis
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Overview

Legg-Calve-Perthes disease occurs when the ball of the thighbone in the hip doesn’t get enough blood, causing the bone to die.[1] Early symptoms may include mildly painful limp, pain down the inner thigh to the knee, some restriction of hip movement, pain at extremes of movement, and tenderness over the hip joint.[2] Treatment may include a brief period of bed rest (1 to 3 days) followed by bracing. Rarely bracing may be required for 2 to 3 years. Chance of recovery (prognosis) varies, but tends to be better for younger patients (e.g., less than 6 years of age). Some people with this syndrome go on to develop degenerative arthritis.[1][2] The cause of the condition is unknown.
Last updated: 1/6/2011

References

  1. Legg-Calve-Perthes disease. MedlinePlus. 2010; http://www.nlm.nih.gov/medlineplus/ency/article/001264.htm. Accessed 1/6/2011.
  2. Legg-Calvé-Perthes disease. Ferri’s Clinical Advisor 2010, 1st ed. Philadelphia, PA: Mosby; 2009;
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Basic Information

  • Genetics Home Reference (GHR) contains information on Legg-Calve-Perthes disease. This website is maintained by the National Library of Medicine.
  • The American Academy of Orthopaedic Surgeons has an information page on Legg-Calvé-Perthes disease. Click on the link above to view this resource page.
  • The National Osteonecrosis Foundation has an information page on Legg-Calve-Perthes disease. Click on the link above to view this information resource.
  • MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic.
  • The Merck Manuals Online Medical Library provides information on this condition for patients and caregivers. 
  • The National Organization for Rare Disorders (NORD) has a report for patients and families about this condition. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.

In Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • MeSH® (Medical Subject Headings) is a terminology tool used by the National Library of Medicine. Click on the link to view information on this topic.
  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Legg-Calve-Perthes disease. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Perthes disease
  • Legg-Calve-Perthes syndrome
  • LCPD
  • Osteochondritis deformans
  • Coxa plana
Related Diseases
  • Osteochondrosis
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.