Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Lymphomatoid papulosis


Other Names for this Disease
  • LyP
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Treatment

Newline Maker

How might lymphomatoid papulosis be treated?

Localized mildly itchy skin lesions may be treated with mid- to high-potency topical steroids to hasten healing, or with more aggressive topical therapies (e.g.,phototherapy) to suppress the disease and the possibility of progression to lymphoma. Low-dose weekly methotrexate has been used to suppress the condition with some success, however the treatment effects are not lasting. Oral psoralen plus UVA phototherapy may also effectively treat and suppresses the disease.[1]

A few reports have found that following treatments may also help with disease suppression:[1]
  • Topical carmustine
  • Topical nitrogen mustard
  • Topical MTX
  • Topical imiquimod cream
  • Intralesional interferon
  • Low-dose cyclophosphamide
  • Chlorambucil
  • Medium-dose UVA-1 therapy
  • Excimer laser therapy
  • Dapsone
Last updated: 6/19/2012

References
  1. Zic JA. Lymphomatoid Papulosis. Medscape Reference. 2012; http://emedicine.medscape.com/article/1098954-overview. Accessed 6/19/2012.


GARD Video Tutorial

  • Finding Treatment Information - A video developed by GARD Information Specialists that explains how you can find information about treatment for a rare disease.

    Finding Treatment Information

Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Lymphomatoid papulosis. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
Other Names for this Disease
  • LyP
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.