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Diseases

Genetic and Rare Diseases Information Center (GARD)

Mantle cell lymphoma


Other Names for this Disease
  • Lymphoma, mantle cell
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Overview

Mantle cell lymphoma (MCL) belongs to a group of diseases known as non-Hodgkin’s lymphomas (NHL). NHL's are cancers that affect the the lymphatic system (part of the immune system). In MCL, there are cancerous B-cells (a type of immune system cell). The cancerous B-cells are within a region of the lymph node known as the mantle zone.[1] Although MCLs are slow-growing cancers, the cancer is usually widespread by the time it is diagnosed. In these situations, treatment must be intensive since MCL can become life threatening within a short period of time.[2][3] MCL accounts for 6% of all NHL's and is mostly found in males during their early 60s.[4][2][3]
Last updated: 4/27/2016

References

  1. Mantle Cell Lymphoma. National Organization for Rare Disorders (NORD). February 2011; http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Mantle%20Cell%20Lymphoma. Accessed 7/11/2011.
  2. O’Connor OA and Vose JM. Mantle Cell Lymphoma: Getting the Facts. Lymphoma Research Foundation.. http://www.lymphoma.org/atf/cf/%7B0363CDD6-51B5-427B-BE48-E6AF871ACEC9%7D/MANTLE%20CELL.PDF. Accessed 7/11/2011.
  3. Non Hodgkin Lymphoma. American Cancer Society. October 2010; http://www.cancer.org/acs/groups/cid/documents/webcontent/003126-pdf.pdf. Accessed 7/11/2011.
  4. Mantle Cell Lymphomas. Lymphomation. June 2011; http://www.lymphomation.org/type-MCL.htm. Accessed 7/11/2011.
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Basic Information

In Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Mantle cell lymphoma. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Lymphoma, mantle cell
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.