Marcus Gunn phenomenon
Other Names for this Disease
- Maxillopalpebral synkinesis
- Familial Marcus Gunn phenomenon (subtype)
- Marcus Gunn syndrome
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 The wink phenomenon may be elicited by opening the mouth, thrusting the jaw to the side, jaw protrusion, chewing, smiling, or sucking. It is usually present at birth and may occur with other eye abnormalities (such as strabismus) or vision problems. Although it usually affects one eye, it can affect both eyes in rare cases. The exact cause is not known. Marcus Gunn phenomenon is generally sporadic, but familial cases with autosomal dominant inheritance have been reported. Treatment is not always needed but may include surgery in more severe cases.Marcus Gunn phenomenon is a rare condition characterized by movement of the upper eyelid in a rapid rising motion (a "wink") each time the jaw moves.
Last updated: 9/1/2015
- Marcus Gunn Phenomenon. National Organization for Rare Disorders (NORD). 2003; http://rarediseases.org/rare-diseases/marcus-gunn-phenomenon/. Accessed 7/1/2009.
- Sean M Blaydon. Marcus Gunn Jaw-winking Syndrome. Medscape Reference. November 30, 2015; http://emedicine.medscape.com/article/1213228-overview.
- Marcus-Gunn syndrome. Orphanet. April 2007; http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN&Expert=91412. Accessed 3/4/2013.
- The National Organization for Rare Disorders (NORD) has a report for patients and families about this condition. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Marcus Gunn phenomenon. Click on the link to view a sample search on this topic.