Monoclonal gammopathy of undetermined significance
Other Names for this Disease
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multiple myeloma, macroglobulinemia, or B-cell lymphoma). MGUS is thought to be a multifactorial condition that is likely associated with the effects of multiple genes in combination with lifestyle and environmental factors. People with MGUS are usually monitored closely to ensure that the levels of monoclonal protein do not rise and other problems do not develop. Those with stable levels of monoclonal protein typically do not require treatment.Monoclonal gammopathy of undetermined significance (MGUS) is a condition in which an abnormal protein called monoclonal protein is detected in the blood. MGUS typically does not cause any problems, although some affected people may experience numbness, tingling or weakness. In some cases, MGUS may progress over time to certain forms of blood cancer (such as
Last updated: 5/8/2015
- Monoclonal gammopathy of undetermined significance (MGUS). Mayo Clinic. May 2013; http://www.mayoclinic.org/diseases-conditions/mgus/basics/definition/con-20026422.
- Suzanne R Fanning, DO. Monoclonal Gammopathies of Uncertain Origin. Medscape Reference. December 2014; http://emedicine.medscape.com/article/204297-overview#a0104.
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- The Merck Manual for health care professionals provides information on Monoclonal gammopathy of undetermined significance.
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Monoclonal gammopathy of undetermined significance. Click on the link to view a sample search on this topic.