Microvillus inclusion disease
Other Names for this Disease
- Davidson disease
- Microvillus atrophy, congenital
- Congenital familial protracted diarrhea with enterocyte brush-border abnormalities
- Intractable diarrhea of infancy
- Congenital familial protracted diarrhea
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total parenteral nutrition. The advent of intestinal transplantation has improved the outlook for these patients. Microvillus inclusion disease is inherited in an autosomal recessive manner.Microvillus inclusion disease is an intestinal disorder characterized by severe, watery diarrhea and an inability of the intestines to absorb nutrients. Symptoms typically develop in the first days (early-onset) or first months (late-onset) of life. Without adequate water and nutrients, children with this condition can become dehydrated, suffer from malnutrition, and fail to grow and develop normally. Management is difficult and relies on
Last updated: 10/5/2011
- Microvillus Inclusion Disease. Children's Hospital of Pittsburgh. December 12, 2010; http://www.chp.edu/CHP/Microvillus. Accessed 10/5/2011.
- Ruemmele FM, Schmitz J, Goulet O. Microvillous inclusion disease. Orphanet. June 2006; http://www.orpha.net/consor/cgi-bin/Disease_Search.php?lng=EN&data_id=2157&Disease_Disease_Search_diseaseGroup=Microvillus-inclusion-disease&Disease_Disease_Search_diseaseType=Pat&Disease(s)/group%20of%20diseases=Microvillus-inclusion-disease&title=M. Accessed 10/5/2011.
- Genetics Home Reference (GHR) contains information on Microvillus inclusion disease. This website is maintained by the National Library of Medicine.
- The National Organization for Rare Disorders (NORD) has a report for patients and families about this condition. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them.
- Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
- The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
- Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
- PubMed is a searchable database of medical literature and lists journal articles that discuss Microvillus inclusion disease. Click on the link to view a sample search on this topic.