Your browser does not support javascript:   Search for gard hereSearch for news-and-events here.

Diseases

Genetic and Rare Diseases Information Center (GARD)

Microvillus inclusion disease


Other Names for this Disease
  • Davidson disease
  • Microvillus atrophy, congenital
  • Congenital familial protracted diarrhea with enterocyte brush-border abnormalities
  • Intractable diarrhea of infancy
  • Congenital familial protracted diarrhea
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Treatment

Newline Maker

How might microvillus inclusion disease be treated?

While different medications have been tried to control the severe diarrhea associated with this condition, none of them have proven effective.[1] Children with microvillus inclusion disease are totally dependent on parenteral nutrition for nourishment. This, however, is not a long-term solution, as children who rely on this type of nutrition are at increased risk for malnutrition, dehydration, infections and liver complications. A more recent and long-term management option involves intestinal (small bowel) transplantation.[1][2] Children with microvillus inclusion disease should be followed by experienced health care providers in a center which specializes in pediatric gastrointestinal disorders.[2] 
Last updated: 6/26/2012

References
  1. Microvillus Inclusion Disease. Children's Hospital of Pittsburgh. December 12, 2010; http://www.chp.edu/CHP/Microvillus. Accessed 10/5/2011.
  2. Ruemmele FM, Schmitz J, Goulet O. Microvillous inclusion disease. Orphanet. June 2006; http://www.orpha.net/consor/cgi-bin/Disease_Search.php?lng=EN&data_id=2157&Disease_Disease_Search_diseaseGroup=Microvillus-inclusion-disease&Disease_Disease_Search_diseaseType=Pat&Disease(s)/group%20of%20diseases=Microvillus-inclusion-disease&title=M. Accessed 10/5/2011.


GARD Video Tutorial

  • Finding Treatment Information - A video developed by GARD Information Specialists that explains how you can find information about treatment for a rare disease.

    Finding Treatment Information

Clinical Trials & Research for this Disease

  • ClinicalTrials.gov lists trials that are studying or have studied Microvillus inclusion disease. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies.
  • The Research Portfolio Online Reporting Tool (RePORT) provides access to reports, data, and analyses of research activities at the National Institutes of Health (NIH), including information on NIH expenditures and the results of NIH-supported research. Although these projects may not conduct studies on humans, you may want to contact the investigators to learn more. To search for studies, enter the disease name in the "Text Search" box. Then click "Submit Query".
Other Names for this Disease
  • Davidson disease
  • Microvillus atrophy, congenital
  • Congenital familial protracted diarrhea with enterocyte brush-border abnormalities
  • Intractable diarrhea of infancy
  • Congenital familial protracted diarrhea
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.