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Diseases

Genetic and Rare Diseases Information Center (GARD)

Mycobacterium Avium Complex


Other Names for this Disease
  • MAC
  • Mycobacterium Avium-Intracellulare
  • MAI
  • Mycobacterium Avium
  • Mycobacterium Avium-Intracellulare infection
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Overview

Mycobacterium avium complex (MAC) refers to infections caused by two types of bacteria: Mycobacterium avium and Mycobacterium intracellulare.[1] MAC primarily affects people with compromised immune systems (for example from AIDS, hairy cell leukemia, or immunosuppressive chemotherapy) or underlying lung disease.[2] Symptoms can be non-specific and may include fever, sweats, weight loss, abdominal pain, fatigue, chronic diarrhea, and anemia. It may cause local disease affecting the central nervous system, lymph nodes, soft tissue, or bones; or, it may cause multi-system disease also affecting other organs and systems.[3][2] MAC is spread when the bacteria, found in water, soil and dust particles, are inhaled or ingested. Treatment for MAC varies depending on the type and may include antibiotics, antituberculosis drugs, and/or surgery.[1][2]
Last updated: 12/21/2015

References

  1. Judith S Currier, MD. Mycobacterium avium complex (MAC) infections in HIV-infected patients. UpToDate. May 2014;
  2. Janak Koirala, MD, MPH, FACP, FIDSA. Mycobacterium Avium-Intracellulare. Medscape Reference. March 2014; http://emedicine.medscape.com/article/222664-overview.
  3. Mycobacterium avium Complex Disease. AETC National Resource Center. April, 2014; http://aidsetc.org/guide/mycobacterium-avium-complex-disease.
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In Depth Information

  • Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss Mycobacterium Avium Complex. Click on the link to view a sample search on this topic.
  • The AIDS Education and Training Center (AETC) offers information on Mycobacterium Avium Complex. Click on the link to view this information page.
Other Names for this Disease
  • MAC
  • Mycobacterium Avium-Intracellulare
  • MAI
  • Mycobacterium Avium
  • Mycobacterium Avium-Intracellulare infection
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.