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Diseases

Genetic and Rare Diseases Information Center (GARD)

Myoclonic epilepsy with ragged red fibers


Other Names for this Disease
  • Merrf syndrome
  • MERRF
  • Myoclonic epilepsy associated with ragged red fibers
  • Fukuhara syndrome
  • Myoencephalopathy ragged-red fiber disease
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Treatment

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How might myoclonic epilepsy with ragged red fibers (MERRF) be treated? 

While there is no cure for MERRF, there are various medications and therapies that can be helpful in managing symptoms. This includes: Antiseizure medications, levetiracetam for myoclonus, physical therapy, and aerobic exercise. Standard medication is used to treat cardiac symptoms. 

Daily use of Coenzyme Q10 and L-carnitine have been of some benefit to individuals. Other supplements that might be utilized include creatinine and lipoic acid.[1]
Last updated: 6/23/2016

References
  1. DiMauro, S. and Hirano, M. MERRF. GeneReviews. January 29, 2015; http://www.ncbi.nlm.nih.gov/books/NBK1520/.


Management Guidelines

  • GeneReviews provides current, expert-authored, peer-reviewed, full-text articles describing the application of genetic testing to the diagnosis, management, and genetic counseling of patients with specific inherited conditions.
Other Names for this Disease
  • Merrf syndrome
  • MERRF
  • Myoclonic epilepsy associated with ragged red fibers
  • Fukuhara syndrome
  • Myoencephalopathy ragged-red fiber disease
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.