Myosin storage myopathy
Other Names for this Disease
- Hyaline body myopathy
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 Myosin storage myopathy is caused by changes (mutations) in the MYH7 gene and is typically inherited in an autosomal dominant manner. Treatment is generally supportive and may include orthopedic treatments, as well as physical, occupational or speech therapy.Myosin storage myopathy is an inherited condition that affects the muscles. Signs and symptoms generally begin during infancy or early childhood; however, some affected people may not develop symptoms until early adulthood and there are even reports of people who are asymptomatic into their 40s. Myosin storage myopathy is primarily characterized by muscle weakness with minimal or very slow progression. As a result, affected people may experience delayed motor milestones (i.e. walking), trouble climbing stairs, difficulty lifting arms above shoulder level, and less commonly, breathing problems.
Last updated: 2/8/2016
- Myosin storage myopathy. Genetics Home Reference. February 2013; http://ghr.nlm.nih.gov/condition/myosin-storage-myopathy.
- Glenn Lopate, MD. Congenital Myopathies. Medscape Reference. August 2014; http://emedicine.medscape.com/article/1175852-overview.
- NINDS Congenital Myopathy Information Page. National Institute of Neurological Disorders and Stroke. October 2015; http://www.ninds.nih.gov/disorders/myopathy_congenital/myopathy_congenital.htm.
- Genetics Home Reference (GHR) contains information on Myosin storage myopathy. This website is maintained by the National Library of Medicine.
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- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
Autosomal dominant myosin storage myopathy
Autosomal recessive myosin storage myopathy
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