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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Neurofibromatosis type 2

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Other Names for this Disease
  • Acoustic neurinoma bilateral
  • Acoustic schwannomas bilateral
  • Bilateral acoustic neurofibromatosis
  • Familial acoustic neurinoma
  • Familial acoustic neuroma
Related Diseases
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Inheritance

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Is neurofibromatosis type 2 inherited?

Neurofibromatosis type 2 (NF2) is inherited in an autosomal dominant manner. This means that a person only needs a change (mutation) in one copy of the responsible gene in each cell to have a genetic predisposition to the tumors associated with NF2. In approximately half of cases, an affected person inherits the mutation from an affected parent. Other cases may result from new (de novo) mutations in the gene; these cases occur in people with no history of the disorder in their family. A person with NF2 has a 50% chance with each pregnancy of passing along the altered gene to his or her child.[1]
Last updated: 7/21/2015

References
  1. D Gareth Evans, MD, FRCP. Neurofibromatosis 2. GeneReviews. August 2011; http://www.ncbi.nlm.nih.gov/books/NBK1201/#nf2.Clinical_Description.


Other Names for this Disease
  • Acoustic neurinoma bilateral
  • Acoustic schwannomas bilateral
  • Bilateral acoustic neurofibromatosis
  • Familial acoustic neurinoma
  • Familial acoustic neuroma
Related Diseases
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.