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Diseases

Genetic and Rare Diseases Information Center (GARD)

PANDAS


Other Names for this Disease
  • Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections
  • Pediatric autoimmune neuropsychiatric disorders associated with Streptococcus infections
  • Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcus
  • Pediatric autoimmune disorders associated with Streptococcus infections
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.

Overview

PANDAS is an acronym for Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcus. It is used to describe a condition in children whose symptoms of obsessive-compulsive disorder (OCD) or a tic disorder (i.e. Tourette syndrome) are worsened by group A streptococcal (GAS) infections. The underlying cause of PANDAS is unclear, but studies suggest that a strep infection causes an abnormal immune response resulting in neuropsychiatric symptoms. The association between PANDAS and GAS is controversial because the cause has not been proven. Management is centered on providing antibiotics for GAS infection, and medication or behavioral therapy for neuropsychiatric symptoms.[1][2]
Last updated: 7/5/2016

References

  1. Michael E Pichichero. PANDAS: Pediatric autoimmune neuropsychiatric disorder associated with group A streptococci. UpToDate. Waltham, MA: UpToDate; June, 2016;
  2. PANDAS: Fact Sheet about Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections. NIMH. August, 2015; http://www.nimh.nih.gov/health/publications/pandas/index.shtml.
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Basic Information

In Depth Information

  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.
  • PubMed is a searchable database of medical literature and lists journal articles that discuss PANDAS. Click on the link to view a sample search on this topic.
Other Names for this Disease
  • Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections
  • Pediatric autoimmune neuropsychiatric disorders associated with Streptococcus infections
  • Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcus
  • Pediatric autoimmune disorders associated with Streptococcus infections
See Disclaimer regarding information on this site. Some links on this page may take you to organizations outside of the National Institutes of Health.