Other Names for this Disease
- Pearson marrow-pancreas syndrome
- Pearson's marrow/pancreas syndrome
- Pearson's syndrome
- Sideroblastic anemia with marrow cell vacuolization and exocrine pancreatic dysfunction
sideroblastic anemia and pancreatic dysfunction resulting in in malabsorption and chronic diarrhea. The features of this progressive disorder may change over time. Individuals who survive beyond infancy often develop the symptoms of Kearns-Sayre syndrome or Leigh syndrome. Pearson syndrome is caused by deletions in mitochondrial DNA. Inheritance is usually sporadic.Pearson syndrome is a mitochondrial disorder characterized by transfusion-dependent
Last updated: 11/21/2011
- Rogers ZR, Quinn CT. Pearson Syndrome . eMedicine. January 25, 2010; http://emedicine.medscape.com/article/957186-overview#showall. Accessed 11/21/2011.
- DiMauro S, Hirano M. Mitochondrial DNA Deletion Syndromes . GeneReviews. May 3, 2011; http://www.ncbi.nlm.nih.gov/books/NBK1203/. Accessed 11/21/2011.
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